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GxP SAP S/4HANA Solution Delivered in Record Time

When a leading biotech faced a failing ERP programme and the imminent shutdown of its legacy PeopleSoft system, Marlborough helped the Executive Board take decisive action. By providing senior CTO expertise, programme leadership, change management, data migration, and specialist SAP skills, Marlborough enabled delivery of a fully operational, GxP-compliant SAP S/4HANA solution in just four months — with zero disruption to critical business operations.

Posted Oct 27, 2025

AT A GLANCE

Pain Points

  • 2 years of stalled ERP progress

  • Failing suppliers 

  • Compliance risk growing

  • Poor data quality 

  • Fragmented teams

  • Escalating costs/ poor ROI

Our Leadership

  • Reset failing programme

  • Led exemplar delivery, reporting directly to CIO/Board 

  • Injected critical SAP subject matter expertise & organisational change management (OCM)

  • Ensured results & lasting impact

Value Delivered

  • ERP Live in 4 months

  • Achieved GxP compliance with clean data & confidence restored

  • Ensured payroll, invoicing & business operations continued seamlessly during ERP transition & beyond.

SITUATION & CLIENT CHALLENGE 

Marlborough was initially engaged to provide Senior Advisory to a leading global R&D biotech that offers accelerated, high-value pipeline co-creation and innovative R&D solutions. For this organisation, like so many others, digital IT enablement was pivotal to achieving corporate objectives, including AI-powered insights, data-driven services, innovative technologies, and resilience against operational and cyber risks.

Consistent with many companies across sectors, ERP was a key system underpinning their business and digital capabilities across functions. The existing UK ERP was end-of-life, and the hosting solution was being decommissioned within five months. To protect continuity and take advantage of next-generation capabilities, the client needed to rapidly implement a new GxP-compliant ERP system while transitioning core business processes.

Without a functioning ERP, it would not have been possible to enact critical financial, quality, manufacturing, procurement, and sales processes. The urgency, coupled with the failure of a prior SAP programme, created significant risk to compliance, resilience, and business continuity.

The stakes were even higher under strict GxP regulatory requirements. Any disruption or data integrity issue could have undermined compliance, quality standards, and customer trust.

OUR LEADERSHIP ROLE & KEY INTERVENTIONS

Recognising these challenges, the client’s senior leadership selected Marlborough as their trusted transformation partner. They wanted a firm that could work alongside permanent project resources, provide senior CTO expertise, and bring proven SAP leadership experience to accelerate and de-risk the programme.

Marlborough’s intervention was pivotal. We halted the failing programme, reset delivery with a clear roadmap, and provided programme leadership and subject matter expertise that enabled a compliant SAP S/4HANA solution to be delivered in just four months.

Programme Reset to Succeed

Injected transformation leadership & programme management: led the initiative end-to-end, from set-up through to service delivery handover.

Restored delivery discipline: re-established focus, aligned resources & introduced robust governance with weekly Executive Board visibility.

Established parallel streams of change across technical, data, integration, security, quality, service design, service transition, training & supplier onboarding. Marlborough structured and governed these streams cohesively, ensuring alignment to outcomes and benefits.

Strengthened operating model: identified & onboarded a new SI, shaped the OP model, & defined the BAU service support model.

Drove outcome-focused delivery: established the critical path plan, clarified ownership, and created Business and IT governance boards to ensure time-boxed decision-making, open communication, and rapid escalation resolution.

Restored Delivery Discipline

Re-established focus & priorities — reset the programme around a clear roadmap, critical path, and outcome-driven milestones.

Aligned resources effectively — optimised use of permanent staff, SI, and Marlborough experts and others to build a cohesive, high-performing team.

Strengthened execution control — introduced structured tracking, proactive risk management, and rapid issue resolution to maintain pace.

Built Board confidence — provided transparent weekly progress updates and decision making that enabled fast decisions and kept delivery on track.

Change Management & Stakeholder Engagement

Injected Organisational Change Management (OCM) skills & expertise — brought proven OCM capabilities to guide stakeholders through the transformation.

Secured executive sponsorship — worked closely with senior leadership to reinforce urgency, priorities, and benefits.

Built cross-functional alignment — engaged finance, quality, procurement, manufacturing, and sales teams to ensure shared ownership.

Drove user adoption — delivered targeted communications, training, and engagement activities to reduce resistance and accelerate acceptance.

Maintained momentum — fostered collaboration across business and IT functions, ensuring issues were surfaced and resolved quickly.

Data Migration, Testing & Cutover

Injected proven tools & techniques — applied Marlborough’s tried-and-tested approaches alongside client processes to drive accountability for delivery and manage dependencies on the critical path.

Ensured rigorous testing & readiness — partnered with client teams to design, build, and transition technology and data with a strong focus on testing and business readiness.

Safeguarded data integrity & compliance — executed data cleansing, migration, and validation, embedding GxP controls to meet stringent life sciences standards.

De-risked cutover — managed a controlled transition that ensured continuity of finance, procurement, quality, and manufacturing processes.

"Marlborough really helped us deliver against our plans. They were engaging, collaborative and helped us drive a critical project to a successful conclusion"

Senior Vice President

Knowledge Transfer

Upskilled IT & business teams — equipped client staff with the knowledge and confidence to operate and extend the SAP S/4HANA solution.

Embedded knowledge transfer — paired Marlborough experts with client resources to build capability throughout the project lifecycle.

Left a sustainable legacy — ensured ongoing ownership by strengthening internal expertise and reducing reliance on external support.

KEY RESULTS & LASTING IMPACT

The programme delivered tangible business outcomes that protected critical operations while creating a stronger, more resilient ERP foundation for the future.
 

SPEED

Delivered a compliant SAP S/4HANA solution in just four months!

COMPLIANCE

Achieved GxP compliance with clean data achieved, confidence restored, resilience built & teams upskilled.

CONTINUITY

Ensured payroll, invoicing & business operations continued seamlessly during ERP transition & beyond.

"Thank you for supporting us on our way forward and in making the right decisions for our company"

SVP Head Global Logistics & Procurement

  • Marlborough’s leadership, pace, and targeted interventions ensured the client not only achieved a safe transition, but also gained lasting business value.
     
  • Delivered at pace: a fully operational GxP-compliant SAP S/4HANA solution in just four months.
     
  • Zero disruption: payroll, invoicing, and critical business operations continued seamlessly during transition.
     
  • Enhanced functionality & efficiency: new ERP capability enabled more streamlined processes, improved metrics, and stronger KPI reporting.
     
  • Strengthened compliance & resilience: embedded GxP standards and controls, reducing operational and regulatory risk.
     
  • Delighted the Board and stakeholders: rapid, compliant delivery enhanced confidence in IT delivery and strengthened credibility.
     
  • Built lasting capability: knowledge transfer and upskilling from Marlborough to client teams ensured sustainable ownership and reduced external dependency.
     

"Marlborough’s leadership has been instrumental in delivering an operational GxP SAP solution into our business in less than 4 months from start to finish… amazing!!!"

Chief Operating Officer (COO)

  • Extended impact: building on UK success, Marlborough subsequently supported ERP deployment to additional locations into 2025, realising significant financial benefits.

Marlborough: Driving Transformation at Pace, Protecting Business Continuity, and Leaving a Sustainable Legacy.